This report describes the rationale, approaches, organization, and resource development leading to a large-scale deletion bin map of the hexaploid wheat genome. Accompanying reports in this issue detail results from chromosome bin-mapping of expressed sequence tags representing genes onto the seven homoeologous chromosome groups and a global analysis of the entire mapped wheat EST data set. Among the resources developed were the first extensive public wheat EST collection. Described are protocols for sequencing, sequence processing, EST nomenclature, and the assembly of (...) ESTs into contigs. These contigs plus singletons were used for selection of distinct sequence motif unigenes. Selected ESTs were rearrayed, validated by 5′ and 3′ sequencing, and amplified for probing a series of wheat aneuploid and deletion stocks. Images and data for all Southern hybridizations were deposited in databases and were used by the coordinators for each of the seven homoeologous chromosome groups to validate the mapping results. Results from this project have established the foundation for future developments in wheat genomics. (shrink)

This book is part of a larger study of the problem of the one and the many in Aristotle's Metaphysics. Although this portion can be read and understood on its own, some remarks about the contents of the two sister volumes will be helpful.

Charles Sanders Peirce (1839-1914) is considered to be among the half dozen most important philosophers the United States has produced. The Charles S. Peirce Sesquicentennial International Congress opened at Harvard University on September 5, 1989 and concluded on the 10th - Peirce's birthday. The Congress was host to approximately 450 scholars from 26 different nations. Papers concerning Peirce's philosophy of science were given at the Congress by representatives from Italy, France, Sweden, Finland, Korea, India, Denmark, Greece, Brazil, Belgium, Spain, Germany, (...) and the United States. The present volume is a compilation of some of the papers that were presented at that Congress. (shrink)

Today most of us are awash with choices. The cornucopia of material goods available to those of us in the developed world can turn each of us into a kid in a candy store; but our delight at picking the prize is undercut by our regret at lost opportunities. And what's the criterion for choosing anything -- material, spiritual, the path taken or not taken -- when we have lost our faith in everything? In The Era of Choice Edward (...) Rosenthal argues that choice, and having to make choices, has become the most important influence in both our personal lives and our cultural expression. Choice, he claims, has transformed how we live, how we think, and who we are.This transformation began in the nineteenth century, catalyzed by the growing prosperity of the Industrial Age and a diminishing faith in moral and scientific absolutes. The multiplicity of choices forces us to form oppositions; this, says Rosenthal, has spawned a keen interest in dualism, dilemmas, contradictions, and paradoxes. In response, we have developed mechanisms to hedge, compromise, and to synthesize. Rosenthal looks at the scientific and philosophical theories and cultural movements that choice has influenced -- from physics to postmodernism, from Disney trailers to multiculturalism. He also reveals the effect of choice on the personal level, where we grapple with decisions that range from which wine to have with dinner to whether to marry or divorce, as we hurtle through lives of instant gratification, accelerated consumption, trend, change, and speed. But we have discovered, writes Rosenthal, that sometimes, we can have our cake and eat it, too. (shrink)

We investigate the notion of conditional probability and the quantum mechanical concept of state reduction in the context of GL spaces satisfying the Alfsen-Shultz condition.

Post-foundational politics and democracy -- Agonism and democracy -- A typology of agonistic democracy -- Agonistic democracy and the question of institutions -- Agonistic democracy and the limits of popular participation -- Populism, representation, and the popular will -- Political liberalism, contingency and agonistic pluralism -- Liberalism, agonism, and democracy.

Heraclitus is famous for affirming contradictions, though most readers do not regard the content of his fragments as contradictory. Examining fragments 1 and 50, this article argues that Heraclitus aims to assert a special class of contradictions, the intrinsic conflict between the content of any universal metaphysical claim and the assertion or reception of that claim. Such contradictions undermine the possibility of metaphysics as a science that knows all things. Second, the article argues that Heraclitus himself embraces this sort of (...) contradiction by making it, as it were, the content of his Logos. Third, the article examines three other solutions to the problem that have been advanced, mostly tacitly, by other philosophers. The article concludes with some steps towards a different way of preserving the possibility of metaphysics. (shrink)

It can be shown that considerable common ground exists between indigenous or traditional theories of contagious disease in Africa, and modern medicine, whether human or veterinary. Yet this is not recognized because of the generally low regard in which the medically trained – whether African or expatriate – hold African traditional medicine. This attitude seems to result from the assumption that African health beliefs are based on witchcraft and related “supernatural” thinking. I argue that this may not be so in (...) the important domain of diseases biomedically classified as contagious; such diseases tend to be understood naturalistically. An accurate understanding of how Africans traditionally interpret contagious diseases of humans and livestock is the foundation for the design and implementation of more effective health programs. (shrink)

Mendler contends that many of the beliefs, tenets, conclusions, and understandings that are widely accepted as “truths” are, in fact, not valid at all. He asserts that we should challenge them all — from Plato on to contemporary theorists in all of those fields — and analyze every element of their conclusions.

This paper addresses a central metaphysical issue that has not been recognized: what kind of entity is a syllogism? I argue that the syllogism cannot be merely a mental entity. Some counterpart must exist in nature. A careful examination of the Posterior Analytics’s distinction between the syllogism of the fact and the syllogism of the reasoned fact shows that we must set aside contemporary logic to appreciate Aristotle’s logic, enables us to understand the validity of the scientific syllogism through its (...) content rather than its form, and explains the priority of the scientific syllogism over other valid syllogisms. The opening chapters of Posterior Analytics II help us to distinguish the entities that scientific syllogism must include as its terms; namely, a genus, an essential nature, and essential attributes of the genus. Often, the attributes are found in closely linked sequences. By exploring why there are such sequences and how they are linked, the paper argues that sequences of genus, nature, and sequential attributes are the basis in nature for the process of reasoning that we call the syllogism: we come to grasp the syllogism over time but the sequences to which it refers exist together in things. So understood, the syllogism, like knowledge of forms and truths, exists in us and in the world. (shrink)

A discussion of American pragmatism through the writings of its three major advocates: Charles S. Peirce, William James, and John Dewey. Examines how each applied pragmatism to, respectively, the theory of reality, the notion of truth, and the concept of the good.

FEW PHILOSOPHERS, NONE APPROACHING HIS STATURE, would agree with Hegel’s claim that we have an ethical duty to marry. More commonly, philosophers sanction marriage as ethically permissible, as Kant does, or even, at least in recent years, reject marriage as ethically illegitimate. Hegel’s view reflects his understanding of the family as a moral institution, that is, an institution in which mere participation is a moral act and, therefore, obligatory. The notion that the family is or, at least, is supposed to (...) be moral has become so deeply ingrained that it may sound perverse to suppose that its morality needs any sort of justification; on the other hand, it is difficult to understand why marriage and family should be obligatory. The first aim of this paper is to answer the question, why does Hegel think that marriage is a moral institution that we have a duty to enter? The issue here is not how to recover or preserve “family values” but why the family has any value at all morally. To refine the issue, I will contrast Hegel’s approach with that of someone who, surprisingly, denies the intrinsic moral value of the family, Aristotle. (shrink)

In the majority of academic institutions nursing and medical students receive a traditional education, the content of which tends to be specific to their future roles as health care professionals. In essence, each curriculum design is independent of each course. Over the last decade, however, interest has been accumulating in relation to interprofessional and multiprofessional learning at student level. With the view that learning together during their student training would not only encourage and strengthen future collaboration in practice settings but (...) also enhance patient care, the University of Dundee decided to run a pilot study to explore shared teaching in ethics between medical and nursing students. This article presents a report on the reasons for selecting health care ethics as a precursor for shared teaching, the educational tool used for the sessions, and the results of student and facilitator evaluation of the short course. Overall, despite problems such as poor attendance by some students, and facilitation and timetable difficulties, most of the feedback from students and facilitators has been positive. In essence the ‘idea’ has gone from strength to strength and there are now three levels of shared teaching in ethics between nursing and medical students, with plans to include further sessions with students from other disciplines. Within the text, ‘health care ethics’ will be referred to as ‘ethics’; nursing students/nurses encompasses midwifery students/midwives. (shrink)